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The Effect of 0.5% Sodium Tetradecyl Sulfate

Sodium tetradecyl sulfate

INTRODUCTION

A venous lake is a small, dark blue, slightly raised, soft lesion that occurs on the exposed skin of elderly people. This lesion is easily compressed, and it is mainly located on the face, ear, lip, neck, forearm and back of hand. It is lined by a single layer of flattened endothelial cells and a thin wall of fibrous tissue. Although it is usually asympto­matic, treatment may be required if there bleeding after trauma to this type of lesion, which can occur frequently, or if the lesion is cosmetically disfiguring. Numerous treatment modalities have been reported in the English Medical literatures, such as surgical excision, laser therapy, infrared coagulation, cryotherapy and sclerotherapy.

Sodium tetradecyl sulfate (STS) is a kind of sclerosing agent that’s been used for the treatment of hemangioma and other vascular conditions. Intravenous injection of STS causes intimal in­flammation and thrombus formation, and these conditions usually occlude the injected vein. Thus, we designed this study to determine the efficacy of injectiong 0.5% STS for treating venous lake lesions.
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