The Effect of 0.5% Sodium Tetradecyl Sulfate: RESULTS
No patients were lost to follow-up. Five venous lakes cleared after a single treatment, four after two treatments, two after three treatments, one after four treatments and one after five treatments. The average number of treatments needed to achieve a complete cure was 2.15 ±1.28 (range 1 to 5) and the average infused volume of STS was 0.09±0.05 cc (range: 0.05 to 0.2). After treatment, all of the patients’ lesions were completely cleared (Fig. 2). No patient experienced any recurrence with a mean follow up of 29.58±13.48 months (range 10~49 months) and there were no side effects such as swelling, inflammation, skin necrosis or hyperpig- mentation. During injection, some patients felt light pain and paresthesia, but this soon disappeared. The details of the long term follow-up results are summarized in Table 1.
Table 1. Summary of clinical history of 12 patients
|
Case no. |
Age/Sex |
Number Site of venous lakes |
Size of each lesion (mm) |
Infused volume* |
Number of treatments |
Remission |
Complicat ions |
Recurrence |
Duration of follow up (months) |
|
1 |
76/F |
Lower lip 1 |
10 |
0.2 |
4 |
Complete |
Absent |
No |
45 |
|
2 |
39/F |
Lower lip 1 |
3 |
0.05 |
2 |
Complete |
Absent |
No |
15 |
|
3 |
40/M |
Lower lip 1 |
3 |
0.05 |
1 |
Complete |
Absent |
No |
10 |
|
4 |
57/F |
Lower lip 1 |
7 |
0.15 |
3 |
Complete |
Absent |
No |
46 |
|
5 |
48/M |
Lower lip 1 |
5 |
0.1 |
2 |
Complete |
Absent |
No |
49 |
|
6 |
71/F |
Lower lip 1 |
3 |
0.05 |
5 |
Complete |
Absent |
No |
36 |
|
7 |
47/M |
Lower lip 1 |
3 |
0.05 |
1 |
Complete |
Absent |
No |
13 |
|
8 |
50/F |
Lower lip 2 |
2, 5 |
0.05, 0.1 |
2 |
Complete |
Absent |
No |
23 |
|
9 |
47/F |
Lower lip 1 |
5 |
0.1 |
3 |
Complete |
Absent |
No |
41 |
|
10 |
72/M |
Lower lip 1 |
3 |
0.05 |
1 |
Complete |
Absent |
No |
35 |
|
11 |
56/F |
Upper lip 1 |
5 |
0.1 |
1 |
Complete |
Absent |
No |
17 |
|
12 |
32/M |
Lower lip 1 |
7 |
0.15 |
1 |
Complete |
Absent |
No |
25 |
Fig. 1. The dilated lumen is lined by a single layer of flattened endothelial cells and the lumen is filled with erythrocytes on the biopsy of case No. 4 (H&E, x400).
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Fig. 2. (A) The venous lake on the lower lip of case No. 8 before sclerotherapy. (B) This photograph shows the clinical appearance 5 weeks after the initial sclerotherapy.







