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The Effect of 0.5% Sodium Tetradecyl Sulfate: RESULTS

No patients were lost to follow-up. Five venous lakes cleared after a single treatment, four after two treatments, two after three treatments, one after four treatments and one after five treatments. The average number of treatments needed to achieve a complete cure was 2.15 ±1.28 (range 1 to 5) and the average infused volume of STS was 0.09±0.05 cc (range: 0.05 to 0.2). After treatment, all of the patients’ lesions were completely cleared (Fig. 2). No patient experienced any recurrence with a mean follow up of 29.58±13.48 months (range 10~49 months) and there were no side effects such as swelling, inflammation, skin necrosis or hyperpig- mentation. During injection, some patients felt light pain and paresthesia, but this soon disappeared. The details of the long term follow-up results are summarized in Table 1.

Table 1. Summary of clinical history of 12 patients

Case no.

Age/Sex

Number Site of venous lakes

Size of each lesion (mm)

Infused volume*

Number of treatments

Remission

Complicat ions

Recurrence

Duration of follow up (months)

1

76/F

Lower lip 1

10

0.2

4

Complete

Absent

No

45

2

39/F

Lower lip 1

3

0.05

2

Complete

Absent

No

15

3

40/M

Lower lip 1

3

0.05

1

Complete

Absent

No

10

4

57/F

Lower lip 1

7

0.15

3

Complete

Absent

No

46

5

48/M

Lower lip 1

5

0.1

2

Complete

Absent

No

49

6

71/F

Lower lip 1

3

0.05

5

Complete

Absent

No

36

7

47/M

Lower lip 1

3

0.05

1

Complete

Absent

No

13

8

50/F

Lower lip 2

2, 5

0.05, 0.1

2

Complete

Absent

No

23

9

47/F

Lower lip 1

5

0.1

3

Complete

Absent

No

41

10

72/M

Lower lip 1

3

0.05

1

Complete

Absent

No

35

11

56/F

Upper lip 1

5

0.1

1

Complete

Absent

No

17

12

32/M

Lower lip 1

7

0.15

1

Complete

Absent

No

25

Fig. 1. The dilated lumen

Fig. 1. The dilated lumen is lined by a single layer of flattened endothelial cells and the lumen is filled with erythrocytes on the biopsy of case No. 4 (H&E, x400).
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Fig. 2. (A) The venous lake

Fig. 2. (A) The venous lake on the lower lip of case No. 8 before sclerotherapy. (B) This photograph shows the clinical appearance 5 weeks after the initial sclerotherapy.

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