The Effect of 0.5% Sodium Tetradecyl Sulfate: DISCUSSION
A venous lake lesion was first described by Bean and Walsh in 1956. It was previously called blueberry on the lip and senile hemangioma of the lip. The lesion is a small, bluish-purple, slightly- raised, soft papule or nodule caused by a localized vascular dilatation. The size of a venous lake varies, but most of them measure 1 to 15 mm. The lesion is usually round or oval, but the larger ones may be irregular. It often occurs on sun-damaged skin and the most common sites are the face, ears and lips.
Histopathologically, a few or multiple large, dilated and irregular thin-walled venules are located in the upper and middle dermis. The venules are lined by a single layer of flattened endothelial cells and a thin wall of fibrous tissue. In some instances, in place of the fibrous tissue, there is a thin irregular noncontinuous layer of smooth muscle. This lesion is thought to occur as a result of deterioration in the connective tissue in the vascular adventitia, as well as in the dermis.
Lakes have been previously treated by surgical excision, laser therapy, infrared coagulation, cryotherapy and sclerotherapy has been pre¬viously reported. All of these methods were regarded as effective by the authors. Although a patient with a venous lake is usually free of symptoms, it must sometimes be treated because of traumatic bleeding, as well as due to cosmetic concerns. Surgical excision is available for venous lakes, but this is considered to be more invasive than sclerotherapy and surgical excision harbors the risk of hemorrhage and scar. Laser therapy may result in skin atrophy, hyperpigmentation, a slight depression of the skin, and scarring and it also incurs high costs to the patient. Cryotherapy may also result in scarring and hyperpigmentation and hypopigmentation. All the lesions we evaluated in this study were small, which was one of the important factors for the choice of treatment. In addtion, sclerotherapy does not present the risk of hemorrhage, it is a less invasive method and it maintains a low cost. kamagra soft tablets
Sclerotherapy refers to the injection of a foreign substance into the lumen of a vessel to cause endothelial and mural change, thrombosis, vessel wall necrosis and subsequent fibrosis. It is a relatively simple, safe, quick and effective treatment for hemangioma and other related conditions. Sclerotherapy is effective for low-flow lesions because the injected sclerosant is diluted less rapidly and it remain in contact with the vessel walls for longer time. A venous lake can be regarded as a low flow vascular lesion as the color of it fades on diascopy and the color reappears slowly after a release of pressure.
