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Antimicrobial Agents and Chemotherapy: Combination PI-Containing Regimen for HIV-Infected, Treatment-Experienced Patients

Combination PI-Containing Regimen for HIV-Infected, Treatment-Experienced Patients Speaker: Robert Schooley, MD, Head of Infectious Diseases and Professor of Medicine, University of Colorado, Denver, Colorado. Based on a preliminary 24-week analysis, amprenavir 600 mg (Agenerase, GlaxoSmithKline)/ritonavir 100 mg (Norvir drug, Abbott) twice daily might be a better treatment regimen than amprenavir 900 mg/ritonavir 100 mg twice [...]

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Antimicrobial Agents and Chemotherapy: Recombinant Protein for Severe Sepsis

Speaker: Steven P. LaRosa, MD, Associate Staff Physician, Department of Infectious Diseases, Cleveland Clinic Foundation, Cleveland, Ohio. Drotreogin alfa activated (Xigris, Lilly), a recombinant form of protein C recently approved by the FDA for the treatment of severe sepsis, markedly reduces the risk of all-cause mortality in adult patients, according to findings from the PROWESS [...]

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Antimicrobial Agents and Chemotherapy: Potent Antibiotic Combination for Resistant S. aureus Bacteremias

Speaker: Joseph L. Gugliotta, MD, Infectious Disease Specialist, Hunterdon Medical Center, Flemington, New Jersey. The combination of quinupristin/dalfopristin (Synercid, Aventis) and vancomycin (Vancocin, Lilly) proved to be highly effective in the treatment of bacteremias caused by oxacillin-resistant Staphylococcus aureus (ORSA) strains, demonstrating enhanced bactericidal activity compared with either antibiotic tested alone.

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Antimicrobial Agents and Chemotherapy

Short-Duration Antimicrobial Therapy for AECB Speaker: Marcus J. Zervos, MD, Clinical Professor of Medicine, Wayne State University School of Medicine, Detroit, Michigan, and William Beaumont Hospital, Royal Oak, Michigan. Five-day therapy with oral telithromycin (Ketek, Aventis), a new ketolide antimicrobial agent, is as effective as standard 10-day treatment with comparators in adult patients with acute [...]

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