Background and Collection of Isolates
From January 1, 2001 to December 31, 2002, R aeruginosa isolates were recovered from patients seen at various centers in Trinidad. Isolates were collected from community sources, (privately operated microbiology laboratories, general practitioners offices, outpatients clinics) and hospitals (specimens from the ICUs, surgical services, nursery, adult and pediatric medical wards, and [...]
The prevalence of resistance of P aeruginosa strains to the nine antimicrobials tested was relatively low among hospital strains. Strains from community sources were fully sensitive to four of the nine drugs. No local or regional data could be found in the literature to which resistance rates among P aeruginosa could be compared. However, increasing [...]
From 650 cultures that were received from participating centers, 554 (85.2%) were recovered on subculture and subsequently confirmed as P aeruginosa. All of the 554 isolates that were confirmed as P aeruginosa produced pyocyanin. Ninety-six of 554 (17.3%) of the isolates were recovered from the ICU, and 10.1% (56/554) from the nursery. Other inpatients services [...]
INTRODUCTION
Pseudomonas aeruginosa is a ubiquitous organism frequently isolated from clinical specimens. Because these organisms are usually inherently resistant to many antimicrobial agents, treatment of pseudomonal infections is usually difficult, and mortality is usually high. This intrinsic resistance is mainly a result of the diffusion barrier of the bacterial outer membrane; amino-acid substitution in the target [...]
INTRODUCTION
Since the introduction of antibiotics medication into clinical use, bacteria have protected themselves by developing antibiotic resistance mechanisms. Multiresistant organisms are diminishing our ability to treat and control the spread of infections. Resistance to antibiotics has undermined the idealistic hope that bacterial infection would cease to be an important cause of death and disease. Indeed, [...]
