HARRIS-BENEDICT EQUATIONS DO NOT ADEQUATELY PREDICT ENERGY: RESULTS
Demographics
A total of 61 patients, of which 66% were female, were included in the study. The primary reason for admission covered a full range of medical conditions (Table 1). Only 3/21 men and 2/40 women were receiving mechanical ventilation during their RMR measurement.
Table 1. Primary Reasons for Admission (Number of Patients)
| Diagnosis |
Men (21) |
Women (40) |
| Cancer |
4 |
1 |
| Cardiovascular/Diabetes 3 |
8 |
|
| Dementia |
2 |
2 |
| Gastrointestinal |
2 |
6 |
| Infection |
7 |
13 |
| Malnutrition |
2 |
|
| Physical Rehabilitation |
1 |
со |
| Pulmonary |
1 |
1 |
| Skin/Joint | CO |
6 |
| Surgery |
2 |
|
The mean age was 79.6+Л8.9 (range 65-102 years). Age was not significantly different by gender (men=78.2+/-7.1 versus women=80.3+/-9.7 years). Also in women, but not men, age was significantly correlated with RMR (-0.408, p=0.009). silagra 100
Body Mass Index
The mean BMI was 21.5+/-4.9 kg/m2—21.8+/-4.7 for men and 21.3+/-5.1 for women. Seven of 21 men and 12/40 women had BMI <18.5 kg/m2, while 10 men and 18 women had BMI in the normal range, and four men and 10 women were either overweight or obese by BMI.
Energy Requirements
Mean RMR for the entire cohort was 1391.9+/-271.4 (range 914-2,361 kcal/day). RMR for the 56 patients who did not require mechanical ventilation during the RMR measurement was 1369.8+/-267.4 kcal/day. Normalized to measured body weight, the RMR was 24.8+Л5 (range 14.2-39.1) kcal/kg/day. Mean Harris-Benedict BEE for the entire cohort was 1149.7+/-183.1 kcal (range 841-1856), and 1146.6+/-187.6 in nonventilated patients. Normalized to measured body weight, the BEE was 20.3+/-2.4 (range 13.9-27.5 kcal/kg/day). canadian antibiotics
RMR was significantly greater than BEE (pO.OOl, paired t-test). Only 16/61 patients (1/21 men and 15/40 women) had RMR within 10% of BEE. Only 2/61 patients had RMR <90% of Harris-Benedict BEE prediction. RMR was 123.5+/-14.7% of Harris-Benedict BEE (range=84-145%) for men, and 120.2+/-19.1% (range 89-173%) for women. Absolute RMR was significantly greater for men than for women (men=1558.4+/-207.5 versus women=1304.6+/-261.7 kcal/day, p=0.0001, ANOVA) but not when normalized to body weight (men=25.3+/-4.8 versus women=24.5+/-5.2).
Figure 1. Frequency Histogram of Measured RMR (Kcal) as Percentage of Harris-Benedict Prediction for Individual Patients
Figure 1 is a frequency histogram, presenting the measured RMR (solid line) as a percentage of the Harris-Benedict prediction (dashed line). The curve from current data is shifted considerably to the right, since 74% of all measurements are >110% BEE. buy antibiotics in canada
