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COMP-angiopoietin 1 Gene Transfer Enhances Cutaneous Wound Healing: RESULTS

Ade-COMP-Ang 1 enhances the rate of wound healing Analysis of the clinical wound healing rate in Ade-COMP-Ang 1-treated and Ade-LacZ-treated groups was performed via digital processing at 0, 3, 7 and 14 days after the wounding. The Ade- COMP-Ang 1-treated group showed 39.5%, 59.3%, and 91.8% reduction of the wound area at day 3, 7, [...]

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COMP-angiopoietin 1 Gene Transfer Enhances Cutaneous Wound Healing: MATERIALS AND METHODS part 2

Histology and immunohistochemistry Three wounds on the back of each rat were sequentially removed from the site at days 3, 7 and 14 after surgery. Each specimen was divided into two equal parts. One half of the specimens were fixed in 4% paraformaldehyde, washed in tap water, dehydrated in a series of graded ethanol solutions, [...]

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COMP-angiopoietin 1 Gene Transfer Enhances Cutaneous Wound Healing: MATERIALS AND METHODS

Adenoviral vectors Recombinant adenoviruses that expressed COMP- Ang 1 or LacZ were constructed using the pAdEasy vector system (Ade-COMP-Ang 1 and Ade-LacZ) (Ade-COMP-Ang 1 and Ade-LacZ were generous gifts from Prof. Gou Young Koh at Korea Advanced Institute of Science and Technology, Daejeon, Korea).

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COMP-angiopoietin 1 Gene Transfer Enhances Cutaneous Wound Healing

INTRODUCTION The closure of cutaneous wounds involves events such as hemorrhage, inflammation, re-epithelializa- tion, granulation tissue formation, and the late remodeling phase of tissue repair. The early and acute phases of repair involve macrophage ac­cumulation, fibroblast ingrowth, matrix deposition, and angiogenesis. These events are triggered by a complex mixture of cytokines and growth factors that [...]

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Developing Teaching Skills during the Pharmacy Practice Residency Program: Limitations

There are many limitations to the research described in this report. First, the built-in limitations of nonvalidated surveys, such as the potential for responder bias, the lack of demonstrable tool reliability, and the possibility of questions being misinterpreted, may have contributed to inaccuracies in the data. Second, some of the data collected relates only to [...]

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Developing Teaching Skills during the Pharmacy Practice Residency Program: Perspectives on the Development

Perspectives on the Development of Teaching Skills The benefits and challenges of using peer teaching strategies have been extensively documented in the medical and nursing literature. Broscious and others7 described a program in which senior students on a clinical unit acted as peer coaches to junior students. Evaluations by both groups indicated that the program [...]

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Developing Teaching Skills during the Pharmacy Practice Residency Program: Design and Implementation

Design and Implementation of Teaching Activities If the addition of a teaching or precepting activity to the residency program is to be considered, proper design and implementation are required. Although it can be argued that no brief experience during a residency can prepare the resident to fulfill the responsibilities of a preceptor, an activity that [...]

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