Beginning with Kennedy’s pioneering studies, topical ALA has been studied in skin because it is a nontoxic, naturally occurring substance that targets cells involved in porphyrin synthesis. This new photosensitizing drug has the ability to penetrate the stratum corneum in a variety of skin tumors, basal cell carcinomas, solar keratoses, and squamous cell carcinoma as [...]
All 10 subjects completed the study. There was a statistically significant reduction in the inflammatory acne lesion count at eight weeks after two sessions of treatment (Table 1) compared to the baseline. Three dermatologists, unaware of the status of treatment, globally assessed clinical improvement; they graded the acne changes without knowledge of the clinical factors. The [...]
Materials We studied 10 healthy subjects of both genders (6 women, 4 men) with an age range of 20 to 29 years (mean age 24.7 years) with acne vulgaris on the face (KAGS; Korean acne grading system grade 3-5). They were enrolled from March 2005 to April 2005. All patients were Fitzpatrick photo skin type II-III [...]
INTRODUCTION Photodynamic therapy (PDT) using aminolevulinic acid (ALA) is a new technique. PDT is being extensively studied in a variety of dermatology settings. These applications include FDA approved treatment of premalignant and malignant skin conditions, as well as off-label uses for photoreiuvination and the treatment of acne vulgaris, sebaceous gland hyoerolasia, telangiectasia, rosacea, and hirsutism. [...]
Targeted patient outcomes can only be achieved if the prescriber accepts and implements the intervention. In this study, workload data were sometimes entered into the workload management system before an issue had been discussed with the prescriber. As a result, the prescriber’s decision was unknown for 11.6% of the interventions at the time of data [...]
This study demonstrated that ambulatory stroke patients experience numerous actual and potential drug-related problems and that pharmacists may be in a key position to identify and resolve these problems. A large number of the pharmacist’s interventions during the study period were related to lack of appropriate pharmacotherapy. Previous research has indicated that 3-hydroxy-3-methylglutaryl-coenzyme A reductase [...]
During the study period, the pharmacist initiated 432 interventions during 153 patient encounters, which represented an average of 2.8 interventions per encounter. The most common interventions were medication counselling, medication reconciliation or follow-up, recommending initiation of pharmacotherapy, and preventing or resolving adverse drug reactions (Figure 1).
