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Augmentation and Combination Pharmacotherapy Trends: RESULTS

Our initial verbal polling of the audience suggested that the “usual” depressed patient in clinical practice would receive two or three psychotropic drugs at any given time after sequential administration. It was clear, among the psychiatrists in the room, that we could not adequately define an “average” depressed patient; however, the question posed suggested that [...]

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Augmentation and Combination Pharmacotherapy Trends: MATERIALS AND METHODS

At the 2005 American Psychiatric Association Annual Meeting in Atlanta, Georgia, an interactive symposium, entitled “Treating Depressive Illnesses: Evidence-Based Updates,” was presented on the topic of the treatment of MDD. One lecturer and co-author (Dr. Schwartz) used an audience-response keypad system to ask the 601-member audience of international psychiatric practitioners about their individual pharmacological practices [...]

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Augmentation and Combination Pharmacotherapy Trends

INTRODUCTION
Depression is a socially debilitating illness, sometimes lifelong, that afflicts the U.S. population with an estimated lifetime risk of 16%. Unfortunately, only a third of depressed patients are receiving any form of treatment, and among the ones who are, only one half to two thirds ever achieve a full response to therapy.

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CLASSIFICATION OF ACUTE RESPIRATORY DISORDERS: DISCUSSION

The most surprising finding of this investigation was that most neonates with respiratory symptoms were not classifiable by standard diagnostic criteria for textbook pulmonary disorders, even applying the broadest definitions. To our knowledge, this is the first attempt to classify acute respiratory disorders in the newborn in three decades in North America. Interestingly, similar to [...]

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CLASSIFICATION OF ACUTE RESPIRATORY DISORDERS: RESULTS

During the one year enrollment period, there were 2805 live-born infants weighing at least 500 grams born without major anomalies in our hospital. We excluded 19 live-born infants from the study because of birth weights below 500 grams (15 infants) or congenital anomalies (four infants). Three were excluded for incomplete data. Of the study population, [...]

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CLASSIFICATION OF ACUTE RESPIRATORY DISORDERS: METHODS

We prospectively studied all infants born at Cook County Hospital, a tertiary perinatal center serving a low-income population, over a 12-month period. About 50-60 % of deliveries had significant perinatal risk factors such as preterm labor, preeclampsia or other significant medical or social problems (E. Swift, MD, personal communication). The birth population was 58% African [...]

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CLASSIFICATION OF ACUTE RESPIRATORY DISORDERS

Experience suggests that many newborn infants with acute respiratory disorders do not fit classic diagnostic patterns. There also is considerable variation among authors about which particular diagnostic criteria should be relied upon to define common disorders, such as respiratory distress syndrome (RDS), also known as hyaline membrane disease (HMD). In 1962, Miller classified patients having [...]

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