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Antimicrobial Resistance Problems in a University Hospital

Antimicrobial Resistance Problems in a University Hospital

INTRODUCTION

Since the introduction of antibiotics medication into clinical use, bacteria have protected themselves by developing antibiotic resistance mechanisms. Multiresistant organisms are diminishing our ability to treat and control the spread of infections. Resistance to antibiotics has undermined the idealistic hope that bacterial infection would cease to be an important cause of death and disease. Indeed, antibiotic resistance increasingly compromises the outcome of many infections that were, until recently, treatable and remain the most common diseases in Africa.

The emergence of antibiotic resistance is primarily due to excessive and often unnecessary use of antibiotics in humans and animals. When faced with a patient suffering from serious infection, the choice of antibiotic canadian depends on clinical judgement and a knowledge of the geographic distribution of resistance among bacteria isolated in the hospital and local community. Thus, continuous monitoring of the pattern of bacterial resistance serves as empirical guide for therapy.

This study was done to examine the resistance patterns of organisms isolated from patients to generic antibiotics used in the treatment of infections in University of Nigeria Teaching Hospital (UNTH), Enugu. The project was divided into three parts:

  • The resistance patterns of the isolates were examined from an overall perspective irrespective of the site of isolation
  • A comparison of the resistance patterns were made between urinary and nonurinary isolates
  • The resistance pattern of urinary isolates from inpatients was compared to that of outpatients.
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