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Aggressive Intensive Care Treatment of Very Elderly Patients with Tetanus Is Justified: RESULTS

According to previous studies showing an increased mortality in elderly patients, we divided the study group according to age (Tables 2 and 3). There was no difference between groups in terms of duration of intubation, hospital stay, and frequency of cardiovas­cular complications. Infectious complications were fairly common in both groups. Two patients died: a 63-year-old woman developed fatal peritonitis due to a perforated duodenal ulcer after 14 days in the intensive care unit; and a 45-year-old woman pre­sented with severe and protracted hypotension that resulted in massive cerebral infarction and death on the 180th day. The eight other patients all experienced uneventful recovery, without any sequelae upon hos­pital discharge.

Table 2—Patients with Generalized Tetanus Younger Than 70 Years of Age

Admission

Intubation

Hospital

Cardiovascular

Patient/Age, у

Year

(Days)

(Days)

Lability

Complications

1/63

1968

14

14

-

Duodena] ulcer with perforation peritonitis; death

4/45

1976

180

180

+

Sustained hypotension with cerebral infarction; death

6/44

1977

45

111

+

Klebsiella
pneumoniae

sepsis

10/23

1982

9

43

+

None

12/61

1987

27

68

+

Staphylococcus
epidermidis

sepsis

Mean ±SD/47.2± 16.1

55* ±71

83* ±65

Median/—

27

68

Table 3—Patients with Generalized Tetanus 70 Years or Older
levitra 10 mg

Admission

Intubation

Hospital

Cardiovascular

Patient/Age, у

Year

(Days)

(Days)

Lability

Complications

3/74

1976

4

50

-

Klebsiella
pneumoniae
pneumonia and sepsis

9/79

1982

20

45

+

GI bleeding, pneumothorax,
Pseudomonas aeruginosa
pneumonia

11/85

1984

55

142

+

Klebsiella
pneumoniae

pneumonia

13/83

1988

90

173

+

None

14/81

1989

45

124

+

None

Mean ±SD/80.4± 4.2

43* ±33

107* ±.56

Median/—

45

124

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