Medical Inspection – Health Blog

Fifty-two patients with the diagnoses and average VC values listed in Table 1 were referred because of symptomatic САН, poorly tolerated and/or ineffective assisted ventilation on body ventilators, or desire to remove or avoid tracheostomy. All were alert and cooperative with functional oropharyngeal muscles and no acute pulmonary disease. All had primarily paralytic/restrictive respira­tory insufficiency [...]

Patients with neuromuscular respiratory insuffi­ciency or restrictive lung disease from thoracic wall deformity may present with subtle symptoms and signs of nocturnal respiratory insufficiency which may not be recognized until the patient develops severe respiratory distress or signs of cor pulmonale. There is increasing interest in the use of noninvasive methods as alternatives to TIPPV [...]

Brinzolamide and dorzolamide are highly specific topical CAIs, which lower intraocular pressure (IOP) by reducing the rate of aqueous humour formation. Although systemic CAIs are the most potent medications for lowering intraocular pressure for primary open-angle glaucoma and other con­ditions with ocular hypertension, many cases with adverse systemic reactions have been reported, including Stevens-Johnson syndrome [...]

Case 1 A 45-year-old Korean man, who had alcoholic liver cirrhosis, suddenly developed blurred vision accompanied by a headache. After emergency ophthalmic surgery, topical brinzolamide was ap­plied to his eyes to control post-operative intra­ocular pressure resulting from pre-existing glau­coma. Two weeks later, after applying brinzolamide 3 times a day, the patient reported pruritic erythematous to [...]

INTRODUCTION Carbonic anhydrase inhibitors (CAI) are com­monly used for lowering the intraocular pressure (IOP) in glaucoma and other ophthalmologic conditions. Carbonic anhydrase inhibitors are sulfo­namide derivatives that are known to cause a range of adverse reactions, including benign transient cutaneous rashes to life-threatening conditions, such as Toxic epidermal necrolysis (TEN). Systemic CAIs are among the [...]

Acrokeratosis paraneoplastica is an example of a paraneoplastic syndrome which reflects an underlying malignancy. The clinical manifestations include palmoplantar keratoderma, violaceous psoriasiform papulosquamous lesions, hyperpigmentation, and nail dystrophy. Acrokeratosis paraneoplastica has a characteristic symmetric bilateral acral distribution, primarily affecting white males of French extraction over 40 years of age. The most common associated neoplasms are [...]

A 63-year-old Korean woman visited our der- matologic clinic with an 11 month history of hyperkeratotic lesions on the palms and soles. The routine laboratory tests, including a complete blood count, liver function tests, and urine analysis revealed values all within the normal range or negative findings. The physical examination revealed yellowish punctuate hyperkeratotic lesions [...]