The sensitivity of a total of 1,718 bacterial isolates from clinical specimens to 20 antimicrobial drugs was studied in 2002 at the University of Nigeria Teaching Hospital, Enugu. The specimens were classified into two groups: urinary and nonurinary specimens. The nonurinary group included wound swabs, blood, body fluids, specimens from respiratory tract, ear, nose and [...]
Out of 120 eligible patients receiving doxorubicin combination therapy at Howard during the study period, 100 patients were evaluable, all of whom were African American (65% women, 35% men, median age 46 years, range 32-84 years). Fifteen patients had hypertension, and 10 were diabetics. None of the patients had history of CHF or coronary artery [...]
INTRODUCTION
Since the introduction of antibiotics medication into clinical use, bacteria have protected themselves by developing antibiotic resistance mechanisms. Multiresistant organisms are diminishing our ability to treat and control the spread of infections. Resistance to antibiotics has undermined the idealistic hope that bacterial infection would cease to be an important cause of death and disease. Indeed, [...]
A retrospective survey of the Howard University Hospital cancer registry during 1997-2001 was conducted to identify all patients who underwent Adriamycin-based combination chemotherapy. Charts were reviewed to find evaluable patients who had records of the cumulative dose of doxorubicin and assessment of clinical cardiac status and echocardiogram both before therapy and at one- to four [...]
Limitations
The cross-sectional design and modest sample size associated with the current study may present as a limitation to the generalizability of the current findings. Although we recognize that the lack of underweight patients in the current study may distinguish this sample from other clinics around the country, we believe, however, that the current study is [...]
INTRODUCTION
In 1957 streptomyces peucetius was isolated from southern Italian soil. The compound 1, 4-hydroxydaunomycin was produced by a variant strain and called Adriamycin (Adria) because of the proximity of the parent strain source to Adriatic Sea. Doxorubicin hydrochloride, the generic name for Adriamycin, has a leading role in the treatment of hematological malignancies and solid [...]
In the current study, we found that almost one-half of adult patients (average age of 37 years) with SCD can be categorized as overweight, and >20% can be categorized as obese. To our knowledge, this is the first study to document a trend towards overweight and obesity in a mature sample of patients with SCD. [...]
